Introduction to Cell Therapy Manufacturing in GMP

Level

Introductory

Format

On-site, practical, including essential theory

Duration

Half-day

Cost

$679

Overview

Cell therapies are reshaping the treatment landscape for diseases once considered untreatable, including several forms of cancer. CAR-T therapies, in particular, have progressed from labour-intensive, manual aseptic processes to increasingly automated and closed manufacturing platforms.

To support this evolving field, CASTL has developed this introductory course focused on cell therapy biomanufacturing. The program provides hands-on experience with the CliniMACS Prodigy system, covering component identification, process flow, tube-set installation, and operation of an end-to-end integrated cell manufacturing platform used in the production of CAR-T, CAR-NK, and stem-cell-based therapies.

This course is offered exclusively at our Richmond (BC) Biomanufacturing Training Facility.

Why It’s Essential

This course builds foundational understanding of the technologies used in cell therapy biomanufacturing and provides hands-on experience that equips participants to work confidently in production environments.

Because limited exposure to complex CGT operations—such as single-use assembly inspection, handling, setup, sampling, and continuous monitoring—can lead to contamination and product loss, strengthening these competencies is essential. By developing practical skills and confidence with the equipment and workflows involved, this course helps reduce the risk associated with one-time batches, scarce raw materials, and the high cost of cell therapy manufacturing.

Learning Objectives

• Gain insights into use, set-up and operation of single-use equipment

• Understand aseptic processing for cell therapy, including sterile welding and sealing operations

• Gain an overview of cell therapy manufacturing process steps from sample collection to cell separation, viral transduction, incubation, and harvest

• Recognize equipment used for quality control and material supply, including flow cytometry and bioreactors for vector supply

Who Should Attend

• Cell therapy manufacturing technicians, QA personnel, Quality Control analysts, manufacturing and operations management, supply-chain, single-use manufacturing system users, vendors, and suppliers.

Participants who successfully complete a theoretical assessment will receive a certificate of completion.