Introduction to mRNA/mRNA-LNP Biomanufacturing

Level

Introductory

Format

On-site, practical, including essential theory

Duration

3 days

Cost

$2,717

Overview

RNA-based biopharmaceuticals are transforming modern medicine. Among them, messenger RNA (mRNA) therapies encapsulated in lipid nanoparticles (LNPs) have emerged as commercial frontrunners, paving the way for a new generation of preventive and therapeutic applications. In response to growing industry demand and the need for skilled professionals, this hands-on introductory course, developed in collaboration with academic and industry experts, strengthens core competencies in mRNA production and LNP formulation by combining essential theoretical knowledge with practical, applied training.

Why It’s Essential

This course provides the essential foundation for industrial-scale mRNA/mRNA-LNP biomanufacturing. The transition from research and development to large-scale production can become a major bottleneck without the right mindset and understanding of biomanufacturing principles. The same applies to all personnel—from operators to facility management—who have not yet been exposed to this emerging class of biopharmaceuticals.

Learning Objectives

• Understand contamination control principles and how to apply these effectively

• Describe the main unit operations used in mRNA-LNP manufacturing, including buffer preparation, aseptic techniques, tangential flow filtration, chromatography, and LNP encapsulation to fill-finish

• Recognize key characteristics and workflows used for mRNA-LNP manufacturing at industrial scale

Who Should Attend

This course is designed for individuals across the biopharmaceutical industry who seek a fundamental understanding of mRNA/mRNA-LNP biomanufacturing, including:

• Professionals working in biomanufacturing, R&D, or process development (from new hires to those experienced in other modalities)

• Teams interested in enhancing their understanding of mRNA and mRNA-LNP production workflows

• Industry members seeking practical insights into mRNA/mRNA-LNP manufacturing processes

Participants who successfully complete a theoretical assessment will receive a certificate of completion.