Course Overview 

Cleanrooms are only as clean as the people and protocols maintaining them. CASTL’s Cleanroom Cleaning and 3-Bucket System solution provides your team with critical knowledge and hands-on skills for executing effective, compliant cleaning in GMP-regulated environments. 

This highly practical session focuses on cleanroom hygiene fundamentals, cleanroom zoning and classifications, proper use of disinfectants and sporicidal agents, and step-by-step training in the 3-bucket cleaning system. Participants leave prepared to uphold your contamination control strategy with confidence and precision. 

Why It’s Essential 

Inadequate cleanroom cleaning is one of the most common sources of regulatory findings and product contamination. This course helps mitigate these risks by ensuring staff are not only trained, but trained to current GMP standards: 

• Prevent product contamination: reduce microbial and particulate risk at the source. 

• Ensure inspection readiness: demonstrate a structured, compliant approach to cleanroom maintenance. 

• Standardize execution: align all staff on consistent SOP-driven practices, including 3-bucket cleaning. 

• Lower operational risk: one cleaning mistake can jeopardize an entire batch or lead to costly shutdowns. 

Investing in proper cleanroom training means fewer deviations, stronger audit outcomes, and higher product integrity. 

What Your Team Will Learn 

Participants will gain the knowledge and confidence to: 

• Understand the role of cleanroom hygiene in maintaining GMP compliance. 

• Identify cleanroom classifications, zones, and associated cleaning protocols. 

• Properly execute the 3-bucket cleaning system using compliant techniques and equipment. 

• Apply correct cleaning movements (e.g., four-fold technique) to maximize coverage and minimize contamination. 

• Use disinfectants and sporicidal agents appropriately as part of a validated cleaning program. 

• Follow documented procedures covering cleaning frequency, environmental monitoring, and deviation prevention. 

Who Should Attend 

This course is designed for employees of regulated manufacturing organizations that operate cleanrooms or classified environments. Recommended for: 

• New industry hires onboarding into GMP roles 

• Cleanroom operators and cleaning staff 

• Production personnel, including operators and supervisors 

• Quality Assurance (QA) and Quality Control (QC) staff involved in monitoring or auditing cleaning practices 

If your operations depend on contamination control, this training ensures your team has the discipline and practical skillset to deliver.